{
  "ticker": "SEPN",
  "name": "Septerna, Inc.",
  "cik": "0001984086",
  "sic": "2834",
  "sic_description": "Pharmaceutical Preparations",
  "source": "SEC XBRL companyfacts",
  "source_url": "https://data.sec.gov/api/xbrl/companyfacts/CIK0001984086.json",
  "as_of": "2026-03-09",
  "note": "Verified SEC companyfacts-derived facts; derived metrics (margins, ratios, free cash flow) are computed from those facts. Descriptive data, not investment advice.",
  "annual": [
    {
      "metric_id": "revenue",
      "label": "Revenue",
      "concept": "RevenueFromContractWithCustomerExcludingAssessedTax",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 1075000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 45951000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "net_income",
      "label": "Net income",
      "concept": "NetIncomeLoss",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:NetIncomeLoss"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 4180000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -71798000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -48879000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "operating_income",
      "label": "Operating income",
      "concept": "OperatingIncomeLoss",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:OperatingIncomeLoss"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 2075000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -80823000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -68297000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "eps_diluted",
      "label": "Diluted EPS",
      "concept": "EarningsPerShareDiluted",
      "unit": "USD/shares",
      "derived": false,
      "source_concepts": [
        "us-gaap:EarningsPerShareDiluted"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 0.29,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -7.26,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -1.1,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "operating_cash_flow",
      "label": "Operating cash flow",
      "concept": "NetCashProvidedByUsedInOperatingActivities",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:NetCashProvidedByUsedInOperatingActivities"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": -38723000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -67470000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 110189000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "capex",
      "label": "Capital expenditures",
      "concept": "PaymentsToAcquirePropertyPlantAndEquipment",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:PaymentsToAcquirePropertyPlantAndEquipment"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 2878000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 2103000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 518000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "assets",
      "label": "Assets",
      "concept": "Assets",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:Assets"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 130867000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 456554000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 596187000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "liabilities",
      "label": "Liabilities",
      "concept": "Liabilities",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:Liabilities"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 20026000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 36507000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 214261000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "equity",
      "label": "Stockholders' equity",
      "concept": "StockholdersEquity",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:StockholdersEquity"
      ],
      "points": [
        {
          "fiscal_year": 2022,
          "period_end": "2022-12-31",
          "value": -44201000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": -38374000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 420047000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 381926000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "cash",
      "label": "Cash and cash equivalents",
      "concept": "CashAndCashEquivalentsAtCarryingValue",
      "unit": "USD",
      "derived": false,
      "source_concepts": [
        "us-gaap:CashAndCashEquivalentsAtCarryingValue"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 88483000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 238196000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 120722000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "free_cash_flow",
      "label": "Free cash flow",
      "concept": "NetCashProvidedByUsedInOperatingActivities - PaymentsToAcquirePropertyPlantAndEquipment",
      "unit": "USD",
      "derived": true,
      "source_concepts": [
        "us-gaap:NetCashProvidedByUsedInOperatingActivities",
        "us-gaap:PaymentsToAcquirePropertyPlantAndEquipment"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": -41601000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -69573000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 109671000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "net_margin",
      "label": "Net margin",
      "concept": "NetIncomeLoss / RevenueFromContractWithCustomerExcludingAssessedTax",
      "unit": "Percent",
      "derived": true,
      "source_concepts": [
        "us-gaap:NetIncomeLoss",
        "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax"
      ],
      "points": [
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -106.37200496180714,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "operating_margin",
      "label": "Operating margin",
      "concept": "OperatingIncomeLoss / RevenueFromContractWithCustomerExcludingAssessedTax",
      "unit": "Percent",
      "derived": true,
      "source_concepts": [
        "us-gaap:OperatingIncomeLoss",
        "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax"
      ],
      "points": [
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -148.63006245783552,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "roe",
      "label": "Return on equity",
      "concept": "NetIncomeLoss / StockholdersEquity",
      "unit": "Percent",
      "derived": true,
      "source_concepts": [
        "us-gaap:NetIncomeLoss",
        "us-gaap:StockholdersEquity"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -17.09284913354934,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -12.798028937542874,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "roa",
      "label": "Return on assets",
      "concept": "NetIncomeLoss / Assets",
      "unit": "Percent",
      "derived": true,
      "source_concepts": [
        "us-gaap:NetIncomeLoss",
        "us-gaap:Assets"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 3.1940825418172647,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": -15.72606964345948,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": -8.19860211645004,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "liabilities_to_equity",
      "label": "Liabilities / equity",
      "concept": "Liabilities / StockholdersEquity",
      "unit": "Ratio",
      "derived": true,
      "source_concepts": [
        "us-gaap:Liabilities",
        "us-gaap:StockholdersEquity"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 0.08691170273802694,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 0.5610013458104449,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    },
    {
      "metric_id": "current_ratio",
      "label": "Current ratio",
      "concept": "AssetsCurrent / LiabilitiesCurrent",
      "unit": "Ratio",
      "derived": true,
      "source_concepts": [
        "us-gaap:AssetsCurrent",
        "us-gaap:LiabilitiesCurrent"
      ],
      "points": [
        {
          "fiscal_year": 2023,
          "period_end": "2023-12-31",
          "value": 16.29707839166908,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745"
        },
        {
          "fiscal_year": 2024,
          "period_end": "2024-12-31",
          "value": 27.77056580278621,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        },
        {
          "fiscal_year": 2025,
          "period_end": "2025-12-31",
          "value": 4.727473513476205,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507"
        }
      ]
    }
  ],
  "quarterly": [
    {
      "metric_id": "revenue",
      "label": "Revenue",
      "concept": "RevenueFromContractWithCustomerExcludingAssessedTax",
      "unit": "USD",
      "source_concepts": [
        "us-gaap:RevenueFromContractWithCustomerExcludingAssessedTax"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "fiscal_quarter": 3,
          "period_label": "2024-Q3",
          "period_end": "2024-09-30",
          "value": 176000.0,
          "filed": "2024-11-20",
          "accession": "0000950170-24-129274",
          "derived": false
        },
        {
          "fiscal_year": 2024,
          "fiscal_quarter": 4,
          "period_label": "2024-Q4",
          "period_end": "2024-12-31",
          "value": 212000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745",
          "derived": true
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 1,
          "period_label": "2025-Q1",
          "period_end": "2025-03-31",
          "value": 219000.0,
          "filed": "2025-05-15",
          "accession": "0000950170-25-072619",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 2,
          "period_label": "2025-Q2",
          "period_end": "2025-06-30",
          "value": 119000.0,
          "filed": "2025-08-11",
          "accession": "0000950170-25-106551",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 3,
          "period_label": "2025-Q3",
          "period_end": "2025-09-30",
          "value": 21495000.0,
          "filed": "2025-11-10",
          "accession": "0001193125-25-273375",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 4,
          "period_label": "2025-Q4",
          "period_end": "2025-12-31",
          "value": 24118000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507",
          "derived": true
        },
        {
          "fiscal_year": 2026,
          "fiscal_quarter": 1,
          "period_label": "2026-Q1",
          "period_end": "2026-03-31",
          "value": 26523000.0,
          "filed": "2026-05-11",
          "accession": "0001193125-26-216759",
          "derived": false
        }
      ]
    },
    {
      "metric_id": "net_income",
      "label": "Net income",
      "concept": "NetIncomeLoss",
      "unit": "USD",
      "source_concepts": [
        "us-gaap:NetIncomeLoss"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "fiscal_quarter": 3,
          "period_label": "2024-Q3",
          "period_end": "2024-06-30",
          "value": -16510000.0,
          "filed": "2024-11-20",
          "accession": "0000950170-24-129274",
          "derived": false
        },
        {
          "fiscal_year": 2024,
          "fiscal_quarter": 4,
          "period_label": "2024-Q4",
          "period_end": "2024-12-31",
          "value": -20668000.0,
          "filed": "2025-03-27",
          "accession": "0000950170-25-045745",
          "derived": true
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 1,
          "period_label": "2025-Q1",
          "period_end": "2025-03-31",
          "value": -21476000.0,
          "filed": "2025-05-15",
          "accession": "0000950170-25-072619",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 2,
          "period_label": "2025-Q2",
          "period_end": "2025-03-31",
          "value": -21476000.0,
          "filed": "2025-08-11",
          "accession": "0000950170-25-106551",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 3,
          "period_label": "2025-Q3",
          "period_end": "2025-06-30",
          "value": -24838000.0,
          "filed": "2025-11-10",
          "accession": "0001193125-25-273375",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 4,
          "period_label": "2025-Q4",
          "period_end": "2025-12-31",
          "value": -10738000.0,
          "filed": "2026-03-09",
          "accession": "0001193125-26-098507",
          "derived": true
        },
        {
          "fiscal_year": 2026,
          "fiscal_quarter": 1,
          "period_label": "2026-Q1",
          "period_end": "2026-03-31",
          "value": -8637000.0,
          "filed": "2026-05-11",
          "accession": "0001193125-26-216759",
          "derived": false
        }
      ]
    },
    {
      "metric_id": "eps_diluted",
      "label": "Diluted EPS",
      "concept": "EarningsPerShareDiluted",
      "unit": "USD/shares",
      "source_concepts": [
        "us-gaap:EarningsPerShareDiluted"
      ],
      "points": [
        {
          "fiscal_year": 2024,
          "fiscal_quarter": 3,
          "period_label": "2024-Q3",
          "period_end": "2024-09-30",
          "value": -8.4,
          "filed": "2024-11-20",
          "accession": "0000950170-24-129274",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 1,
          "period_label": "2025-Q1",
          "period_end": "2025-03-31",
          "value": -0.49,
          "filed": "2025-05-15",
          "accession": "0000950170-25-072619",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 2,
          "period_label": "2025-Q2",
          "period_end": "2025-06-30",
          "value": -0.56,
          "filed": "2025-08-11",
          "accession": "0000950170-25-106551",
          "derived": false
        },
        {
          "fiscal_year": 2025,
          "fiscal_quarter": 3,
          "period_label": "2025-Q3",
          "period_end": "2025-09-30",
          "value": 0.18,
          "filed": "2025-11-10",
          "accession": "0001193125-25-273375",
          "derived": false
        },
        {
          "fiscal_year": 2026,
          "fiscal_quarter": 1,
          "period_label": "2026-Q1",
          "period_end": "2026-03-31",
          "value": -0.19,
          "filed": "2026-05-11",
          "accession": "0001193125-26-216759",
          "derived": false
        }
      ]
    }
  ]
}