{
  "cik": 1894562,
  "cik_padded": "0001894562",
  "entityName": "Prime Medicine, Inc.",
  "fiscal_years": [
    {
      "accn": "0001628280-26-013569",
      "filed": "2026-03-03",
      "fiscal_year": 2025,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "revenue": "USD",
        "stockholders_equity": "USD",
        "total_assets": "USD",
        "total_liabilities": "USD"
      },
      "fundamentals": {
        "capex": 4531000.0,
        "cash": 63032000.0,
        "eps_diluted": -1.35,
        "free_cash_flow": -167095000.0,
        "net_income": -201142000.0,
        "operating_cash_flow": -162564000.0,
        "operating_income": -208350000.0,
        "revenue": 4632000.0,
        "stockholders_equity": 120868000.0,
        "total_assets": 342733000.0,
        "total_liabilities": 221865000.0
      },
      "period_end": "2025-12-31",
      "ratio_units": {
        "leverage": "ratio",
        "revenue_growth_yoy": "ratio",
        "roa_avg2y": "ratio",
        "roa_period_end": "ratio",
        "roe_avg2y": "ratio",
        "roe_period_end": "ratio"
      },
      "ratios": {
        "leverage": 1.8355975113346792,
        "revenue_growth_yoy": 0.5527991954408313,
        "roa_avg2y": -0.6283321436771466,
        "roa_period_end": -0.5868766649257585,
        "roe_avg2y": -1.468098694606539,
        "roe_period_end": -1.6641460105238772
      }
    },
    {
      "accn": "0001628280-26-013569",
      "filed": "2026-03-03",
      "fiscal_year": 2024,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "revenue": "USD",
        "stockholders_equity": "USD",
        "total_assets": "USD",
        "total_liabilities": "USD"
      },
      "fundamentals": {
        "capex": 7294000.0,
        "cash": 182476000.0,
        "eps_diluted": -1.65,
        "free_cash_flow": -130159000.0,
        "net_income": -195882000.0,
        "operating_cash_flow": -122865000.0,
        "operating_income": -202467000.0,
        "revenue": 2983000.0,
        "stockholders_equity": 153149000.0,
        "total_assets": 297508000.0,
        "total_liabilities": 144359000.0
      },
      "period_end": "2024-12-31",
      "ratio_units": {
        "leverage": "ratio",
        "roa_avg2y": "ratio",
        "roa_period_end": "ratio",
        "roe_avg2y": "ratio",
        "roe_period_end": "ratio"
      },
      "ratios": {
        "leverage": 0.9426049141685549,
        "roa_avg2y": -0.7973070606216636,
        "roa_period_end": -0.6584091856353441,
        "roe_avg2y": -1.3687513101809796,
        "roe_period_end": -1.279028919548936
      }
    },
    {
      "accn": "0001628280-26-013569",
      "filed": "2026-03-03",
      "fiscal_year": 2023,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "stockholders_equity": "USD",
        "total_assets": "USD",
        "total_liabilities": "USD"
      },
      "fundamentals": {
        "capex": 8724000.0,
        "cash": 41574000.0,
        "eps_diluted": -2.18,
        "free_cash_flow": -174136000.0,
        "net_income": -198133000.0,
        "operating_cash_flow": -165412000.0,
        "operating_income": -204792000.0,
        "stockholders_equity": 133071000.0,
        "total_assets": 193851000.0,
        "total_liabilities": 60780000.0
      },
      "period_end": "2023-12-31",
      "ratio_units": {
        "leverage": "ratio",
        "roa_avg2y": "ratio",
        "roa_period_end": "ratio",
        "roe_avg2y": "ratio",
        "roe_period_end": "ratio"
      },
      "ratios": {
        "leverage": 0.4567486529747278,
        "roa_avg2y": -0.7150686167477195,
        "roa_period_end": -1.0220891303114248,
        "roe_avg2y": -0.8818825791548067,
        "roe_period_end": -1.488926963801279
      }
    },
    {
      "accn": "0001628280-25-008884",
      "filed": "2025-02-28",
      "fiscal_year": 2022,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "stockholders_equity": "USD",
        "total_assets": "USD",
        "total_liabilities": "USD"
      },
      "fundamentals": {
        "capex": 16095000.0,
        "cash": 187620000.0,
        "eps_diluted": -4.19,
        "free_cash_flow": -147922000.0,
        "net_income": -121821000.0,
        "operating_cash_flow": -131827000.0,
        "operating_income": -116544000.0,
        "stockholders_equity": 316270000.0,
        "total_assets": 360314000.0,
        "total_liabilities": 44044000.0
      },
      "period_end": "2022-12-31",
      "ratio_units": {
        "leverage": "ratio",
        "roa_avg2y": "ratio",
        "roa_period_end": "ratio",
        "roe_avg2y": "ratio",
        "roe_period_end": "ratio"
      },
      "ratios": {
        "leverage": 0.13926075821291933,
        "roa_avg2y": -0.36794478759231014,
        "roa_period_end": -0.3380967711496084,
        "roe_avg2y": -1.5224770355558332,
        "roe_period_end": -0.38518038384924275
      }
    },
    {
      "accn": "0001628280-24-008116",
      "filed": "2024-03-01",
      "fiscal_year": 2021,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "stockholders_equity": "USD",
        "total_assets": "USD",
        "total_liabilities": "USD"
      },
      "fundamentals": {
        "capex": 4150000.0,
        "cash": 185420000.0,
        "eps_diluted": -14.19,
        "free_cash_flow": -38232000.0,
        "net_income": -165367000.0,
        "operating_cash_flow": -34082000.0,
        "operating_income": -84474000.0,
        "stockholders_equity": -156240000.0,
        "total_assets": 301856000.0,
        "total_liabilities": 62296000.0
      },
      "period_end": "2021-12-31",
      "ratio_units": {
        "roa_period_end": "ratio",
        "roe_avg2y": "ratio"
      },
      "ratios": {
        "roa_period_end": -0.5478340665747906,
        "roe_avg2y": 2.148990916297384
      }
    },
    {
      "accn": "0001628280-23-007266",
      "filed": "2023-03-09",
      "fiscal_year": 2020,
      "form": "10-K",
      "fundamental_units": {
        "capex": "USD",
        "cash": "USD",
        "eps_diluted": "USD/shares",
        "free_cash_flow": "USD",
        "net_income": "USD",
        "operating_cash_flow": "USD",
        "operating_income": "USD",
        "revenue": "USD",
        "stockholders_equity": "USD"
      },
      "fundamentals": {
        "capex": 639000.0,
        "cash": 36975000.0,
        "eps_diluted": -1.91,
        "free_cash_flow": -6183000.0,
        "net_income": -3410000.0,
        "operating_cash_flow": -5544000.0,
        "operating_income": -932000.0,
        "revenue": 5210000.0,
        "stockholders_equity": 2338000.0
      },
      "period_end": "2020-12-31",
      "ratio_units": {
        "net_margin": "ratio",
        "operating_margin": "ratio",
        "roe_avg2y": "ratio",
        "roe_period_end": "ratio"
      },
      "ratios": {
        "net_margin": -0.654510556621881,
        "operating_margin": -0.17888675623800385,
        "roe_avg2y": 26.23076923076923,
        "roe_period_end": -1.4585115483319075
      }
    },
    {
      "accn": "0001628280-23-007266",
      "filed": "2023-03-09",
      "fiscal_year": 2019,
      "form": "10-K",
      "fundamental_units": {
        "stockholders_equity": "USD"
      },
      "fundamentals": {
        "stockholders_equity": -2598000.0
      },
      "period_end": "2019-12-31",
      "ratios": {}
    }
  ],
  "latest_filing": {
    "accn": "0001628280-26-013569",
    "filed": "2026-03-03",
    "form": "10-K"
  },
  "note": "Static grepcent export of verified SEC companyfacts-derived values. Monetary values are raw reported units from grepcent's resolved facts; no scaling and no FX conversion. Capex, dividends, and buybacks are reported as positive outflow magnitudes. ROE/ROA include both period-end basis (site-consistent) and average-of-two-years basis where the prior-year denominator exists.",
  "schema_version": "1",
  "sic": "2836",
  "sic_description": "Biological Products, (No Diagnostic Substances)",
  "source_urls": {
    "sec_companyfacts": "https://data.sec.gov/api/xbrl/companyfacts/CIK0001894562.json",
    "sec_submissions": "https://data.sec.gov/submissions/CIK0001894562.json"
  },
  "ticker": "PRME"
}
